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Keep track of Closely (2)diazepam will boost the amount or effect of midazolam intranasal by influencing hepatic/intestinal enzyme CYP3A4 metabolism.
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Breastfeeding Administration to nursing women isn't advisable as dihydrocodeine could be secreted in breast milk and should lead to respiratory melancholy while in the infant.
Adjunct use, if apprehension, anxiousness or acute tension reactions current prior to endoscopic procedures
cobicistat will raise the level or impact of diazepam by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Watch Intently. A reduced dose of diazepam might be needed
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This medication can impair cognitive purpose and might have an effect on a affected person's ability to generate safely. This class of drugs is while in the listing of medicine A part of regulations underneath 5a from the Highway Site visitors Act 1988. When prescribing this medication, people must be explained to:
diazepam will raise the stage or effect of lemborexant by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Watch Intently. Reduced nightly dose of lemborexant advised if coadministered with weak CYP3A4 inhibitors. See drug monograph for specific dosage modification.
crizotinib boosts levels of diazepam by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Watch. Dose reduction may very well be necessary for coadministered medication that are predominantly metabolized by CYP3A.
cannabidiol will boost the level or effect of diazepam by impacting hepatic enzyme CYP2C19 metabolism. Modify Therapy/Keep track of Carefully. Take into consideration reducing the dose of delicate CYP2C19 substrates, as clinically acceptable, when coadministered with cannabidiol.
A Patient Data Leaflet (PIL) is often a doc A part of the offer of the medication that gives precise specifics of that medication and its use. It features information regarding dose check here and administration in the medication, warnings and precautions and possible side effects.
hydrocortisone will reduce the extent or outcome of diazepam by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Watch.
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